Description
Lipofectamine®MessengerMAXmRNATransfectionReagentdeliversamazingtransfectionefficiencyinneuronsandabroad-spectrumofprimarycells,enablingimprovedapplicationoutcomesandmore
BIOLOGicallyrelevantresearch.That"sbecauseournovellipidnanoparticletechnologyisoptimizedtodeliverthehighestamountofmRNAposs
IBLewithoutthenuclearentrystepthatisrequiredwithDNA.
Successfullytransfectmorepredictivecellmodelswithareagentthatprovides:
•Amazingtransfectionefficiencyinneuronsandprimarycelltypes
•Fasterproteinexpressionwithnoriskofgenomicintegration
•Upto10xhighercleavageusingmRNACRISPRs
EnablehightransfectionefficiencyinnovelgenomeeditingapplicationsLipofectamine®MessengerMAX™reagenthelpsincreasethelikelihoodofsuccessfulcleavageandrecombinationwithGeneArt®CRISPRNucleasemRNAthroughhighlyefficienttransfection,ultimatelymaximizingtheefficiencyofgeneticmodificationsandsimplifyingthedownstreamprocesses.
Efficientlytransfectdifficult-to-transfectcellsLipofectamine®MessengerMAX™reagentisdesignedtotransfectahigheramountofmRNAintoneuronsandabroadspectrumofdifficult-to-transfectprimarycells.Thiseliminatestheneedforelectroporationorviruses,andprovidesa>2-foldimprovementintransfectionefficiencycomparedtootherlipidbasedreagents.
LeverageadvantagesofmRNAtransfectionTransfectionofmRNAdoesnotrequirenuclearuptake,whichresultsinfasterproteinexpressionthanDNAtransfectionsincetranslationofmRNAoccursinthecytoplasm.Also,mRNAhasnoriskofgenomicintegrationandtransfectionefficiencyiscellcycleindependent.
ForResearchUseOnly.Notforuseindiagnosticprocedures.